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The Telegraph

Research shows that all adults can reduce the risk of heart attack with a daily blood pressure pill

The study found that all adults would take a daily blood pressure pill to reduce their risk of heart attack. A major study from the University of Oxford found that lowering blood pressure was protective even when it was within good health. Described as a “paradigm shift,” the study found that a single daily dose reduced the risk of serious cardiovascular disease by about 10 percent. The results were the same regardless of which person’s blood pressure was started. The results, published in The Lancet, show that millions of potentially unlicensed people are currently eligible for hypertension medications, including commonly prescribed medications such as Ramipril, which are sold under various beta-blockers of the Altace-Amlodipine brand. : An estimated 14 million people in the UK have high blood pressure, and five million people are diagnosed with the disease, according to the British Heart Foundation. Medical guidelines state that only individuals with high blood pressure above 140/90 mm Hg should usually be considered for hypertension. However, a new study of 340,000 people in 48 randomized clinical trials found that the relative increase or decrease in an individual’s blood pressure determines their risk of heart attack or stroke rather than the level itself. The authors call for a change in guidelines so that people are blocked from taking anti-hypertensive drugs simply because their blood pressure is not high enough or they have not had cardiovascular events before. Professor Kazem Rahimi, who led the study, told The Telegraph: “Antihypertensive drugs are a preventative measure, regardless of your blood pressure. Most people probably do not need it. The authors stopped calling on all adults to start taking pills, saying that spending on the NHS could have consequences, and that the discomfort could outweigh the benefits for people at very low risk of cardiovascular disease. Professor Rahimi added. “At the population level, if you treat everyone, you will have an average relative risk reduction of 10 percent. That’s great, but it’s nothing but factoring. ” He said that many patients currently taking antihypertensive drugs are combined, often up to three drugs a day, which means that the protective effect is significantly greater. He added that doctors should take into account the apparently healthy blood pressure when deciding to prescribe medication, instead assessing the patient’s risk of heart attack or stroke using factors such as cholesterol levels, age and evidence of diabetes. In most parts of the Western world, the leading cause of death is heart disease and stroke, and it is widely accepted that antihypertensive drugs protect against the latter. However, the use of drugs in people with normal or only mild high blood pressure has been hotly debated, and their studies have led to conflicting conclusions. For the new analysis, experts collected data from 157,728 participants with a preliminary diagnosis of cardiovascular disease, and 186,988 without such a diagnosis. Each group was then divided into seven subgroups based on systolic blood pressure levels. Four years later, 42,324 participants had at least one major cardiovascular event. But for every 5 mm Hg drop in systolic blood pressure, the risk of stroke or heart failure drops by 13 percent, ischemic heart disease by 8 percent, and death from cardiovascular disease by 5 percent. The benefits of treatment do not vary depending on whether the person has a history of cardiovascular disease. Ox Einab Biddle, co-author at Oxford, said: “People may be considered for lowering blood pressure because of their cardiovascular risk, rather than focusing on blood pressure as a qualifying factor or target for treatment. “We need to provide good guidelines for reducing the risk of cardiovascular disease, including exercise, nutrition, smoking cessation, and medication if necessary.” Professor Sir Nilesh Samani, Medical Director of the British Heart Foundation, said in the study: “There are benefits to lowering blood pressure, whether you already have heart disease or not.” This study shows that lowering blood pressure, even if it is in the normal range, is associated with fewer heart attacks. “Strikes.”

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